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MD&IT № 2 2024

Original Research

A mathematical model for predicting the decline in estimated glomerular filtration rate at 12 months after parathyroidectomy in patients with primary hyperparathyroidism

Background. Primary hyperparathyroidism (PHPT) is an endocrine disease characterized by excessive production of parathyroid hormone (PTH) and elevated or high-normal blood calcium levels caused by primary pathology of the parathyroid glands. The "classic" complication of PHPT is a decrease in the kidneys filtration function. Parathyroidectomy (PTE) reduces the risks of further deterioration in filtration function; however, in some cases, this is not achieved.
Aim. To develop a mathematical model...