2022
MD&IT №3 2022
Here we describe building a control impact intended to medically suppress tumor growth. The synthesis of control has been carried out using the method of linearization of a nonlinear system with state feedback. As a result of the study, a control law was obtained that provides the system with local stability, which translates into cessation of tumor growth in physical sense. The adequacy of the tumor growth model is achieved by constructing it using a self-organization algorithm with trend reser...
MD&IT №3 2022
Causative relationships of microbiota with the human’s health and diseases are one of the most challenging issues in modern microbiology. Progress in this field could provide new tools for diagnosis, prophylaxis, and treatment. A new automated approach is proposed, as an addition to the methods of multidimensional statistical analysis. This approach is based on a planar projection of multidimensional analytical data and is distinguished by technological simplicity and clarity of the process of operational...
MD&IT №3 2022
New measures to decrease the burden from cardiovascular morbidity are of great socio-economic importance. The aim of the study was to create artificial intelligence technology incorporating various methods and approaches for presenting and using knowledge to assess and predict individual risks of developing cardiovascular events. The following risk presenting models were used: scoring system, multivariate Weibull and logistic regression, artificial neural networks; an ontological approach for ex...
MD&IT №3 2022
Information technologies in modern continuous professional education (CPE) of medical workers are playing an increasingly active role, becoming the basis for the training organization. Aiming to substantiate the strategy for the further development of CPE, we conducted a questionnaire survey of doctors (n=211) immersed in new forms of training using distance learning technologies. Furthermore, regulatory documents were provided that should become a basis for creating conditions f...
MD&IT №3 2022
The problem of early and timely accurate diagnosis of rare hereditary diseases is global. The use of physician-assisted computer systems could solve it. There are various foreign medical decision support systems. However, there are currently no domestic functioning systems to resolve these issues.
The aim of this study is to improve the timeliness and accuracy of making a correct diagnosis in patients with signs of hereditary lysosomal storage diseases using an intelligent computer decision support...
The aim of this study is to improve the timeliness and accuracy of making a correct diagnosis in patients with signs of hereditary lysosomal storage diseases using an intelligent computer decision support...
MD&IT №3 2022
It is very important to balance the processes of creating the simplest and most effective predictive models in medicine. The predictors in the model determine its quality and practical relevance but selecting them is not always easy. The aim of the study is to compare different methods of prediction selection to create medical prognostic models.
Methods. We compare simple methods, such as correlation, predictor filtering based on basic statistics, and Hosmer-Lemeshow univariate analysis, with more...
Methods. We compare simple methods, such as correlation, predictor filtering based on basic statistics, and Hosmer-Lemeshow univariate analysis, with more...
MD&IT №3 2022
There is a trend in the healthcare of the Russian Federation for the development and implementation of various information systems, including medical information systems of medical organizations (MIS MO), aimed automation of diagnostic, treatment, administrative, auxiliary and other processes, as well as radiological information systems (RIS), designed to automate the service of radiation diagnostics and radiology. Many of the currently utilized MIS were developed 10 and more years ago, are base...
MD&IT №2 2022
The success and wide-range applications of artificial intelligence (AI) technologies and, in particular, deep learning neural networks methods have led us to a clear understanding of two main problems: the problem of errors (the reliability problem) and the problem of explicitly explaining the decisions made by AI (the explanability problem). These problems are closely related: unexplained AI errors can happen again and again. This is completely unacceptable from the pers...
MD&IT №2 2022
Auscultation is a classic method of examining patients with respiratory and cardiovascular pathologies. Auscultation is a subjective method, its diagnostic accuracy is highly dependent on the doctor’s experience. Electronic stethoscopes can increase the volume of audio recordings, eliminate noise, and store and transmit sound to a computer or smartphone. Wavelet transform, Butterworth filter, low and high pass filters are used to filter the resulting audio recordings. Machine learning methods, w...
MD&IT №2 2022
Background. Long-term outcomes of screening programs are challenging to evaluate in randomized clinical trials. The role of predictive modeling is becoming increasingly popular in oncology. Modeling the interventions consequences in oncology is based, among other things, on the use of toolkits, denoted by the term «mathematical oncology» Aim. To study approaches to modeling screening scenarios for breast cancer, aimed at developing tools to support medical decision-making in the healthcare syste...
MD&IT №2 2022
Currently, there are no unified methodological approaches to diagnose certain diseases, syndromes, symptoms, where distant diagnostics and telemedicine-based treatment prescription are legal and feasible. There are limited and empirically generated lists of pathological conditions, accounting for possible risks. The development of regulatory and legal support for telemedicine-based medical care should be based on a scientific approach, providing for safety and quality assurance. Objective: to de...
MD&IT №2 2022
Background. Considering the growing interest of researchers and clinical specialists in algorithms for processing medical data, the prospects for the applied application of such approaches have significantly increased, primarily, involving the use of deep neural networks in the tasks of detecting pathological areas. However, the use of such approaches is associated with a low level of localization accuracy, insufficient to translate the developments into the field of assistive systems for making...
MD&IT №2 2022
The article proposes technique and results for pre-project research and design of automated information systems in relation to business process management systems of medical organizations on the example of monitoring the implementation of regulations at the departments of nephrology and hemodialysis. When developing the system, an original method of system analysis and modeling of business processes was used based on the experience of the divisions of a private network medical company working in...
MD&IT №2 2022
The article considers the provisions of the draft convention on improving supranational legal regulation in the Eurasian Economic Union (EEU) in the field of healthcare in the context of the development of innovative digital technologies. Specific proposals on the content of the project’s draft were formed, as well as individual proposals were identified on separate convention sections.
MD&IT №1 2022
Hypertension is a complex cardiovascular condition, defined as an abnormally high blood pressure. Such long-term and consistent increase in blood pressure could result in coronary heart disease, stroke, kidney damage and other serious debilitating conditions. Complication rate from hypertension depends on how well you can predict and prevent those complications, considering individual patient’s risks. Several mathematical models and computer algorithms that are currently used for these purposes ...
MD&IT №1 2022
The rationale for use of artificial intelligence (AI) in radiology departments to analyze medical images in real-life clinical practice was studied in a multicenter prospective trial. This was a part of the “Experiment on the use of innovative technologies in the field of computer vision for the analysis of medical images and further use in the healthcare system of Moscow” taking place in 2020. The trial included 18 different AI systems and 538 participating radiologists, all working wit...
MD&IT №1 2022
Background. Remote follow-up of patients with chronic non-communicable diseases is an increasingly popular and one of the most fast-growing telemedicine branches, mainly due to COVID-19 pandemic. There are certain premises for a wider and more routine use of telemedicine, one of them being coverage of telemedical consultations by the government insurance program. Aim. To test a remote self-control program for patients with chronic non-infectious diseases who are followed-up by the doctors of the...
MD&IT №1 2022
Here we present the key aspects of the fully automated APACHE II scale calculation development. We reviewed implementation opportunities for modern technological solutions in intensive care units. Successful experience of utilizing the clinical decision support system „PHILIPS Digital Resuscitation” for analysis, prognosis and patient data management is described in details. The digital algorithm for automated calculation of the clinical scale used in anesthesiology and intensive care department...
MD&IT №1 2022
In this study we evaluated operability of a multicomponent system consisting of ECG recorders (made by different manufacturers), signal conversion drivers (matching layers) provided by ECG equipment vendors according to a single technical task, an ECG signal processing and visualization program. Such system registers and processes ECG signal by means of the software unit integrated into the regional medical information system (RMIS). System performance evaluation was carr...
MD&IT №1 2022
Here we describe the possibilities of joint use of agent-based modeling and location intelligence based on geoinformation technologies for solving epidemiological problems. This approach has an important advantage allowing close to real-life epidemic progression visualization (hepatitis A) in the “digital twin” of the city. The instrument we developed could be used for both research and practical purposes, as well as for managerial decision-making.
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